Litcius/Paper detail

ER stress as a sentinel mechanism for ER Ca2+ homeostasis

Tadashi Makio, Junsheng Chen, Thomas Simmen

2024Cell Calcium70 citationsDOIOpen Access PDF

Abstract

signaling, diseases such as muscular defects (e.g., from mutated selenoprotein N, SEPN1/SELENON), or diabetes (e.g., from mutated PERK) are the result.

Topics & Concepts

Mechanism (biology)HomeostasisStress (linguistics)Cell biologyChemistryBiophysicsBiologyPhysicsPhilosophyQuantum mechanicsLinguisticsEndoplasmic Reticulum Stress and DiseaseNeuroscience and Neuropharmacology ResearchCardiac electrophysiology and arrhythmias