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Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Xiaobing Wang, Fucheng Yin, Ming Huang, Neng Jiang, Jinshuai Lan, Ling‐Yi Kong

2020RSC Medicinal Chemistry48 citationsDOIOpen Access PDF

Abstract

might be a hopeful multitarget drug candidate with possible impact on Alzheimer's disease therapy.

Topics & Concepts

DonepezilMonoamine oxidaseCholinesteraseDiseaseChromoneMedicinePharmacologyBiologyInternal medicineEnzymeDementiaBiochemistryGeneticsCholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionComputational Drug Discovery Methods
Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease | Litcius