Acute cardiovascular effects of 4th generation electronic cigarettes and combusted cigarettes: implications for harm reduction
Randy Nguyen, Isabelle Ruedisueli, Karishma Lakhani, Joyce Ma, Holly R. Middlekauff
Abstract
We found that nicotine, not the non-nicotine constituents in tobacco cigarette (TC) or electronic cigarette (EC) emissions, may be the instigator of the acute, potentially adverse, changes in hemodynamics and heart rate variability (HRV) that were recorded several minutes after tobacco product use. Furthermore, acute EC use produced an abnormal HRV pattern associated with increased cardiac risk in people who chronically smoke ECs and produced similar hemodynamic increases compared with acute TC use in people who chronically smoke TCs, including people who are dual users.
Topics & Concepts
NicotineHeart rateMedicineHeart rate variabilityBlood pressureTobacco smokeHemodynamicsSmoking cessationInternal medicineCardiologyPhysiologySmokeEndocrinologyAnesthesiaEnvironmental healthChemistryOrganic chemistryPathologyHeart Rate Variability and Autonomic ControlSmoking Behavior and CessationBehavioral Health and Interventions