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The Link between Periodontal Disease and Oral Cancer—A Certainty or a Never-Ending Dilemma?

Zinovia Surlari, Dragoș Ioan Virvescu, Elena-Raluca Baciu, Roxana-Ionela Vasluianu, Dana Gabriela Budală

2021Applied Sciences16 citationsDOIOpen Access PDF

Abstract

Periodontal disease can have a substantial systemic influence on the body that extends beyond the oral cavity and can lead to local inflammation, bone damage, and tooth loss. A great number of studies suggest that periodontitis and oral cancer are linked, however it is unclear if specific periodontal bacteria promote the development of systemic illness. The mediators of the relationship between those two pathologies are still being discovered, but the research findings indicate the existence of a correlation. Additional research, including confounding factors, is needed to strengthen this link.

Topics & Concepts

PeriodontitisMedicineDiseaseOral cavityPeriodontal diseaseSystemic inflammationDilemmaCancerChronic periodontitisDentistryInflammationImmunologyPathologyInternal medicineEpistemologyPhilosophyOral microbiology and periodontitis researchOral Health Pathology and TreatmentHIV/AIDS oral health manifestations
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