Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease
Sushant K. Shrivastava, Avhad Ashok Nivrutti, Bhagwati Bhardwaj, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Manish Tripathi, Poorvi Saraf
Topics & Concepts
ChemistryAcetylcholinesterasePharmacologyPharmacophoreIn vivoTacrineVirtual screeningDrug discoveryBiochemistryEnzymeMedicineBiologyBiotechnologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsChemical synthesis and alkaloids