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Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease

Sushant K. Shrivastava, Avhad Ashok Nivrutti, Bhagwati Bhardwaj, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Manish Tripathi, Poorvi Saraf

2022Journal of Molecular Structure23 citationsDOI

Topics & Concepts

ChemistryAcetylcholinesterasePharmacologyPharmacophoreIn vivoTacrineVirtual screeningDrug discoveryBiochemistryEnzymeMedicineBiologyBiotechnologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsChemical synthesis and alkaloids
Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease | Litcius