Stress Distribution of the Tibiofemoral Joint in a Healthy Versus Osteoarthritis Knee Model Using Image-Based Three-Dimensional Finite Element Analysis
Kulchamai Thienkarochanakul, Akbar A. Javadi, Mohammad Akrami, Joseph Robert Charnley, Abdelmalek Benattayallah
Abstract
Abstract Purpose Osteoarthritis (OA) is one of the most common pathological conditions to affect the human knee joint. In order to analyse the biomechanical causes and effects of OA, accessing the internal structures such as cartilage or the menisci directly is not possible. Therefore, computational models can be used to study the effects of OA on the stresses and strains in the joint and the susceptibility to deformations within the knee joint. Methods In this study, a three-dimensional finite element model of a knee complex was constructed using MRI scans. Medical image processing software was used to create accurate geometries of bones, articular cartilages, menisci, patella, patella tendon and all the relevant ligaments. Finally, a 3D model of OA knee joint was created with a few changes to the cartilage. The cartilage was thinned, and the material properties were altered in order to simulate OA in the joint. 3D gait measurements were analysed to define loading and boundary conditions. Results The developed model analysed the possibility of osteoarthritis. It was shown that the medial regions of cartilage layers and menisci in the knee joint sustain higher values of stress for OA conditions, while for the healthy knee, the stresses are more evenly distributed across the cartilage in the medial and lateral regions. Conclusion The results suggest that any treatment for knee osteoarthritis should focus more on the medial region of the tibiofemoral cartilage in order not to cause degradation.