PIGF and Flt-1 on the surface of macrophages induces the production of TGF-β1 by polarized tumor-associated macrophages to promote lung cancer angiogenesis
Xianglong Kong, Jianlong Bu, Junhui Chen, Boxiong Ni, Bicheng Fu, Fucheng Zhou, Sainan Pang, Jian Zhang, Shidong Xu, Changjun He
Topics & Concepts
AngiogenesisCancer researchPlacental growth factorTransforming growth factorChemistryCytokineTumor microenvironmentFlow cytometryCell biologyVascular endothelial growth factorMolecular biologyImmunologyBiologyTumor cellsVEGF receptorsImmune cells in cancerAngiogenesis and VEGF in CancerTGF-β signaling in diseases