FtsE, the Nucleotide Binding Domain of the ABC Transporter Homolog FtsEX, Regulates Septal PG Synthesis in <i>E. coli</i>
Sunanda Mallik, Hiren Dodia, Arup Ghosh, R. Srinivasan, Liam Good, Sunil K. Raghav, Tushar Kant Beuria
Abstract
. We further demonstrated that septal PG synthesis is independent of FtsE ATPase activity and FtsX. These observations suggest that the FtsEX complex plays a role during septal PG hydrolysis, whereas FtsE alone coordinates septal PG synthesis. Our study indicates that FtsE plays a role in coordinating septal PG synthesis with bacterial cell division.
Topics & Concepts
TransporterATP-binding cassette transporterNucleotideDomain (mathematical analysis)GeneticsBiologyCell biologyGeneChemistryMathematicsMathematical analysisBacterial Genetics and BiotechnologyAntibiotic Resistance in BacteriaEscherichia coli research studies