Tumor-derived exosomes drive pre-metastatic niche formation in lung via modulating CCL1+ fibroblast and CCR8+ Treg cell interactions
Ming Wang, Zhongyu Qin, Jiajia Wan, Yan Yan, Xixi Duan, Xiaohan Yao, Ziming Jiang, Wenqing Li, Zhihai Qin
Topics & Concepts
MicrovesiclesFibroblastNicheCancer researchImmunotherapyLungTreg cellDendritic cellMedicineImmunologyT cellBiologyImmune systemCell culturemicroRNAInternal medicineGeneIL-2 receptorGeneticsBiochemistryEcologyExtracellular vesicles in diseaseSingle-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers