Preparation of a cattle bone collagen peptide–calcium chelate by the ultrasound method and its structural characterization, stability analysis, and bioactivity on MC3T3-E1 cells
Hongru Zhang, Liwei Qi, Xiaodan Wang, Yujie Guo, Jiqian Liu, Yang Xu, Chengjiang Liu, Chunhui Zhang, Aurore Richel
Abstract
) and altered the cell cycle. Significantly, CP-Ca-US enhanced calcium absorption by interacting with calcium-sensing receptors and promoted the mineralization of MC3T3-E1 cells. This study provides the scientific basis for applying the ultrasound method to prepare peptide-calcium chelates and clarifies the positive role of chelates in bone building.
Topics & Concepts
ChelationCalciumChemistryPeptideBiophysicsMineralization (soil science)OsteoblastBiochemistryNuclear chemistryInorganic chemistryNitrogenIn vitroOrganic chemistryBiologyProtein Hydrolysis and Bioactive PeptidesCollagen: Extraction and CharacterizationMeat and Animal Product Quality