Cordycepin ameliorates acute hypobaric hypoxia induced blood-brain barrier disruption, and cognitive impairment partly by suppressing the TLR4/NF-κB/MMP-9 pathway in the adult rats
Peng Liu, Lei Pan, Lei Cui, Tianzuo Li, Sheng Zhao, Yanting Hu, Xiaomei Tao, Hui Deng, Jingwen Jiang, Bin-Jiang Zhao, Yong Wang, Xinying Xue
Topics & Concepts
NeuroinflammationMorris water navigation taskPharmacologyNeuroprotectionTLR4CordycepinBlood–brain barrierHypoxia (environmental)MedicineEvans BlueChemistryHippocampusInternal medicineInflammationCentral nervous systemBiochemistryOxygenOrganic chemistryHigh Altitude and HypoxiaNeuroscience of respiration and sleepNeonatal and fetal brain pathology