Ligustilide covalently binds to Cys703 in the pre-S1 helix of TRPA1, blocking the opening of channel and relieving pain in rats with acute soft tissue injury
Kaixue Zhang, Wenjuan Liu, Fukui Shen, Guoqing Luan, Yanqi Han, Jun Xu, Cheng Fu, Weidong Wu, Yuanyuan Hou, Min Jiang, Min Jiang, Gang Bai, Gang Bai
Topics & Concepts
Blocking (statistics)PharmacologyMedicineAcute painChemistryAnesthesiaComputer scienceComputer networkIon Channels and ReceptorsTraditional Chinese Medicine AnalysisGinseng Biological Effects and Applications