Plumbagin promotes mitochondrial mediated apoptosis in gefitinib sensitive and resistant A549 lung cancer cell line through enhancing reactive oxygen species generation
Munmun Panda, Surya Kant Tripathi, Bijesh Kumar Biswal
Topics & Concepts
PlumbaginApoptosisA549 cellDAPIReactive oxygen speciesCancer cellViability assayGefitinibBiologyMolecular biologyMTT assayCytotoxicityChemistryAnnexinCytotoxic T cellCancer researchCell biologyBiochemistryCancerIn vitroReceptorEpidermal growth factor receptorGeneticsBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsSynthesis of Indole Derivatives