Enhanced mitophagy mediated by the YAP/Parkin pathway protects against DOX-induced cardiotoxicity
Dandan Xiao, Wenguang Chang, Wei Ding, Yu Wang, Hongge Fa, Jianxun Wang
Topics & Concepts
ParkinMitophagyCardiotoxicityAutophagyDoxorubicinApoptosisCell biologyCancer researchChemistryActivator (genetics)PharmacologyPINK1BiologyMedicineChemotherapyBiochemistryToxicityReceptorInternal medicineParkinson's diseaseDiseaseOrganic chemistryAutophagy in Disease and TherapyChemotherapy-induced cardiotoxicity and mitigationUbiquitin and proteasome pathways