One-step isothermal amplification strategy for microRNA specific and ultrasensitive detection based on nicking-assisted entropy-driven DNA circuit triggered exponential amplification reaction
Changjing Yuan, Jie Fang, Xizi Luo, Yang Zhang, Guorong Huang, Xiaojun Zeng, Ke Xia, Mengya Li, Xueping Chen, Yang Xiang, Marc Lamy de la Chapelle, Weiling Fu
Topics & Concepts
Loop-mediated isothermal amplificationChemistryMultiple displacement amplificationDNADetection limitPrimer (cosmetics)microRNAEntropy (arrow of time)Computational biologyCombinatorial chemistryBiological systemBiophysicsPolymerase chain reactionGeneBiochemistryChromatographyBiologyPhysicsThermodynamicsDNA extractionOrganic chemistryAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulationRNA Interference and Gene Delivery