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HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription

Peng Huang, Scott A. Peslak, Ren Ren, Eugene Khandros, Kunhua Qin, Cheryl A. Keller, Belinda Giardine, Henry W. Bell, Xianjiang Lan, Malini Sharma, J.R. Horton, Osheiza Abdulmalik, Stella T. Chou, Junwei Shi, Merlin Crossley, Ross C. Hardison, Xiaodong Cheng, Gerd A. Blobel

2022Nature Genetics51 citationsDOIOpen Access PDF

Topics & Concepts

EnhancerBiologyTranscription factorFetal hemoglobinTranscription (linguistics)GATA1RepressorGlobinRegulation of gene expressionCell biologyMolecular biologyGeneGeneticsFetusPhilosophyLinguisticsPregnancyHemoglobinopathies and Related DisordersErythrocyte Function and PathophysiologyEpigenetics and DNA Methylation
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription | Litcius