PI-RADS Version 2.1 for Prostate MRI Interpretation: Associations of Study Quality and Cancer Detection Metrics—A Systematic Review and Meta-Analysis
Andrea Nedelcu, Benedict Oerther, Alexander Benkendorff, Stephan Dieckbreder, Guido Schwarzer, Georgios Agrotis, Ivo G. Schoots, Rami El Matine, Michel Eisenblaetter, August Sigle, Hannes Engel, Fabian Bamberg, Matthias Benndorf
Abstract
Background: Estimates of outcome metrics for PI-RADS version 2.1 (v2.1) have shown substantial heterogeneity, possibly relating to risks of bias in the relevant literature.
Topics & Concepts
MedicineProstate cancerBivariate analysisLogistic regressionRisk assessmentCancer detectionOncologyInternal medicineReceiver operating characteristicMeta-analysisCancerSensitivity (control systems)StatisticsMEDLINEProstateMultivariate analysisTest (biology)ConfoundingInformation biasMultivariate statisticsPredictive value of testsPublication biasFalse Negative ReactionsEpidemiologyCut-pointDiagnostic testQuality (philosophy)Diagnostic accuracyRandom effects modelProstate Cancer Diagnosis and TreatmentRadiomics and Machine Learning in Medical ImagingColorectal Cancer Screening and Detection