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Lessons learned from understanding chemotherapy resistance in epithelial tubo-ovarian carcinoma from BRCA1and BRCA2mutation carriers

Cécile Le Page, Setor Amuzu, Kurosh Rahimi, Walter H. Gotlieb, Jiannis Ragoussis, Patricia N. Tonin

2020Seminars in Cancer Biology33 citationsDOI

Topics & Concepts

BiologyGenome instabilityHomologous recombinationDNA repairCancer researchDNA damageOvarian carcinomaSerous fluidOlaparibChemotherapyMutationGermline mutationRAD51BRCA2 ProteinOvarian cancerGenePoly ADP ribose polymerasePolymeraseGeneticsDNACancerBiochemistryPARP inhibition in cancer therapyOvarian cancer diagnosis and treatmentBRCA gene mutations in cancer
Lessons learned from understanding chemotherapy resistance in epithelial tubo-ovarian carcinoma from BRCA1and BRCA2mutation carriers | Litcius