Photochemical Reaction of <i>N</i>,<i>N</i>‐Dimethylanilines with N‐Substituted Maleimides Utilizing Benzaldehyde as the Photoinitiator

Abstract

Abstract Photoorganocatalysis constitutes a powerful domain of photochemistry and organic synthesis. The scaffold of pyrrolo[3,4‐c]quinolinoles exhibits interesting and potent inhibition against various enzymes, making them really promising pharmaceutical targets. Herein, we describe a photochemical methodology for the reaction of N , N ‐dimethylanilines with N‐substituted maleimides, utilizing benzaldehyde as the photoinitiator. A variety of substituted N , N ‐dimethylanilines and N‐substituted maleimides were converted into the corresponding adducts in moderate to high yields.

Topics & Concepts