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GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses

Zhongyou Li, Katja Koeppen, Victoria Holden, Samuel L. Neff, Liviu Cengher, Elora G. Demers, Dallas L. Mould, Bruce A. Stanton, Thomas H. Hampton

2021mSystems18 citationsDOIOpen Access PDF

Abstract

GEO archives transcriptomic data from over 5,800 microbial experiments and allows researchers to answer questions not directly addressed in published papers. However, less than 4% of the microbial data sets include the sample group annotations required for high-throughput reanalysis.

Topics & Concepts

AnnotationTranscriptomeWorkflowData miningGene AnnotationSample (material)Computer scienceComputational biologyGauge (firearms)BiologyInformation retrievalBioinformaticsGeneDatabaseGene expressionGeneticsGeographyPhysicsThermodynamicsGenomeArchaeologyGenomics and Phylogenetic StudiesBiomedical Text Mining and OntologiesMicrobial Community Ecology and Physiology