Feedback amplification of senolysis using caspase-3-cleavable peptide-doxorubicin conjugate and 2DG
Jong Cheol Lee, Gui Chul Kim, Na Kyeong Lee, Seong Who Kim, Young Seok Cho, Seung Woo Chung, Yoon Se Lee, Hyo Won Chang, Youngro Byun, Sang Yoon Kim
Topics & Concepts
Cancer researchSenescenceTargeted therapyDoxorubicinCancerMetastasisApoptosisCytotoxic T cellCombination therapyRadiation therapyChemotherapyIn vitroBiologyMedicinePharmacologyInternal medicineBiochemistryAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranosticsTelomeres, Telomerase, and Senescence