Self-delivery of a metal-coordinated anti-angiogenic nanodrug with GSH depleting ability for synergistic chemo-phototherapy
Fukai Zhu, Cailin Huang, Yanling Lin, Yang Li, Ruiqin Tu, Weihong Lu
Abstract
experiments validated the highly effective accumulation at tumor sites, potent tumor growth inhibition, and inappreciable systemic toxicity. The tumor microenvironment-responsive coordination-driven self-assembled biomimetic nanodrug may hold potential applications in tumor theranostics.
Topics & Concepts
PhotosensitizerChemistryGlutathioneMetalDrug deliveryDrugCancer researchPharmacologyBiophysicsBiochemistryPhotochemistryMedicineOrganic chemistryEnzymeBiologyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisNanoparticle-Based Drug Delivery