Litcius/Paper detail

Hydrogels for the treatment of rheumatoid arthritis

Jiafeng Yi, Yubo Liu, Hongbin Xie, Haoming An, Chao Li, Xing Wang, Wei Chai

2022Frontiers in Bioengineering and Biotechnology41 citationsDOIOpen Access PDF

Abstract

Rheumatoid Arthritis is a universal disease that severely affects the normal function of human joints and the quality of life. Millions of people around the world are diagnosed with rheumatoid arthritis every year, carrying a substantial burden for both the individual and society. Hydrogel is a polymer material with good mechanical properties and biocompatibility, which shows great potential in the treatment of rheumatoid arthritis. With the progress of tissue engineering and biomedical material technology in recent years, more and more studies focus on the application of hydrogels in rheumatoid arthritis. We reviewed the progress of hydrogels applied in rheumatoid arthritis in recent years. Also, the needed comprehensive performance and current applications of therapeutic hydrogels based on the complex pathophysiological characteristics of rheumatoid arthritis are also concluded. Additionally, we proposed the challenges and difficulties in the application of hydrogels in rheumatoid arthritis and put forward some prospects for the future research.

Topics & Concepts

Rheumatoid arthritisSelf-healing hydrogelsMedicineArthritisImmunologyEngineeringChemical engineeringRheumatoid Arthritis Research and TherapiesHER2/EGFR in Cancer ResearchIntramuscular injections and effects