Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
Fatao Luo, Gang Yang, Xia Bai, Deyu Yuan, Ling Li, Diyue Wang, LU Xiao-xiang, Yiran Cheng, Yuchun Wang, Xu Song, Yongyun Zhao
Topics & Concepts
ImmunotherapyBlockadeInternalizationAptamerPD-L1Cancer immunotherapyCancer researchChemistryImmune checkpointChimera (genetics)Fusion proteinGene silencingImmune systemCellBiologyReceptorImmunologyMolecular biologyBiochemistryRecombinant DNAGeneCAR-T cell therapy researchAdvanced biosensing and bioanalysis techniquesImmunotherapy and Immune Responses