Advances in the synthesis of heterocycles bearing an endocyclic urea moiety
Аndrey V. Smolobochkin, Almir S. Gazizov, А. Р. Бурилов, Mikhael Pudovik, Оleg G. Sinyashin
Abstract
The review systematizes and summarizes data on the synthesis of structurally diverse cyclic ureas published over the last 10 years. Saturated and unsaturated monocyclic ureas, as well as fused heterocycles containing one urea moiety, are considered. Data on the biological activity of selected compounds of this type are provided. The synthetic approaches to cyclic carbamides are classified in terms of the reaction type and the source of a carbonyl group. The bibliography includes 235 references.
Topics & Concepts
ChemistryMoietyUreaCombinatorial chemistryOrganic chemistryStereochemistryChemical Synthesis and AnalysisCarbon dioxide utilization in catalysisFluorine in Organic Chemistry