Interrogation of the mammalian gut–brain axis using LC–MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models
Thomas D. Horvath, Sigmund J. Haidacher, Melinda A. Engevik, Berkley Luck, Wenly Ruan, Faith D. Ihekweazu, Meghna Bajaj, Kathleen M. Hoch, Numan Oezguen, Jennifer K. Spinler, James Versalovic, Anthony M. Haag
Topics & Concepts
OrganoidBiologyIn vivoMetabolomicsSpecific-pathogen-freeGastrointestinal tractGut floraPathogenMicrobiologyCell biologyComputational biologyBioinformaticsBiochemistryImmunologyGeneticsVirusGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders