Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
Nils B. Leimkühler, Hélène F.E. Gleitz, Ronghui Li, Inge Snoeren, Stijn Fuchs, James S. Nagai, Bella Banjanin, King H. Lam, Thomas Vogl, Christoph Kuppe, Ursula Stalmann, Guntram Büsche, Hans Kreipe, Ines Gütgemann, Philippe Krebs, Yara Banz, Peter Boor, Evelyn Wing‐Yin Tai, Tim H. Brümmendorf, Steffen Koschmieder, Martina Crysandt, Eric M. Bindels, Rafael Kramann, Ivan G. Costa, Rebekka K. Schneider
Topics & Concepts
BiologyDruggabilityMyelofibrosisStromal cellBone marrowCancer researchProgenitor cellCell biologyHaematopoiesisImmunologyStem cellGeneticsGeneMyeloproliferative Neoplasms: Diagnosis and TreatmentKruppel-like factors researchImmune cells in cancer