A simple and general strategy for postsurgical personalized cancer vaccine therapy based on an injectable dynamic covalent hydrogel
Zhentao Yu, Yudi Xu, Haochen Yao, Xinghui Si, Guofeng Ji, Dong Si, Jiayu Zhao, Zhaohui Tang, Xuedong Fang, Wantong Song, Xuesi Chen
Abstract
and elicits robust tumor-specific immune responses. Thus, it effectively inhibits the postoperative growth of the residual tumor in several murine tumor models. This simple and personalized method to develop cancer vaccines may be promising in developing clinically relevant strategies for postoperative cancer treatment.
Topics & Concepts
Simple (philosophy)Cancer therapyComputer scienceMedicineChemistryCancerComputational biologyBiologyInternal medicinePhilosophyEpistemologyCAR-T cell therapy researchImmunotherapy and Immune Responses3D Printing in Biomedical Research