Litcius/Paper detail

Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease

Kamilia M. Amin, Doaa E. Abdel Rahman, Heba Abdelrasheed Allam, Haidy H. El-Zoheiry

2021Bioorganic Chemistry49 citationsDOI

Topics & Concepts

ChemistryAcetylcholinesteraseAcetamideCoumarinIC50Docking (animal)StereochemistryActive siteEnzymeDonepezilIn vivoIn silicoIn vitroBiochemistryOrganic chemistryGeneDiseaseDementiaBiologyMedicinePathologyNursingBiotechnologyCholinesterase and Neurodegenerative DiseasesSynthesis and biological activityComputational Drug Discovery Methods