Mitochondria-targeting peptide SS-31 attenuates ferroptosis via inhibition of the p38 MAPK signaling pathway in the hippocampus of epileptic rats
Xue Liu, Feiyu Wang, Song Chi, Tao Liu, Hailin Yang, Ru-jie Zhong, Xiaoyu Li, Jing Gao
Topics & Concepts
p38 mitogen-activated protein kinasesGPX4Lipid peroxidationMAPK/ERK pathwayMitochondrionGlutathionePilocarpineCell biologyReactive oxygen speciesChemistryHippocampusOxidative stressInternal medicineEndocrinologyBiologyPharmacologySignal transductionEpilepsyBiochemistryGlutathione peroxidaseSuperoxide dismutaseMedicineNeuroscienceEnzymeFerroptosis and cancer prognosisMicroRNA in disease regulationRNA modifications and cancer