The rate and nature of mitochondrial DNA mutations in human pedigrees
Erla R. Árnadóttir, Kristjan H. S. Moore, Valdís B. Guðmundsdóttir, S. Sunna Ebenesersdóttir, Kamran Guity, Hákon Jónsson, Kāri Stefánsson, Agnar Helgason
Topics & Concepts
BiologyMitochondrial DNAGeneticsGermlinePedigree chartPoint mutationMutation ratemtDNA control regionMutationAlleleNegative selectionCoding regionSelection (genetic algorithm)GeneGenomeHaplotypeArtificial intelligenceComputer scienceMitochondrial Function and PathologyMetabolism and Genetic DisordersMetabolomics and Mass Spectrometry Studies