Effect of l-carnitine on cardiotoxicity and apoptosis induced by imatinib through PDGF/ PPARγ /MAPK pathways
Heba H. Mansour, Shereen M. El kiki, Amel B. Ibrahim, Mervat M. Omran
Topics & Concepts
CarnitineMalondialdehydePlatelet-derived growth factor receptorEndocrinologyChemistryApoptosisGlutathioneInternal medicineSuperoxide dismutaseMAPK/ERK pathwayImatinibCardiotoxicityTyrosine kinaseMedicinePharmacologyKinaseReceptorGrowth factorOxidative stressBiochemistryToxicityMyeloid leukemiaEnzymeChronic Myeloid Leukemia TreatmentsChemotherapy-induced cardiotoxicity and mitigationPI3K/AKT/mTOR signaling in cancer