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Live-Cell Imaging and Quantification of PolyQ Aggregates by Stimulated Raman Scattering of Selective Deuterium Labeling

Kun Miao, Lu Wei

2020ACS Central Science77 citationsDOIOpen Access PDF

Abstract

investigations.

Topics & Concepts

HuntingtinBiophysicsChemistryHuntingtin ProteinProtein aggregationRaman scatteringFluorescenceRaman spectroscopyIsotopic labelingFluorescence-lifetime imaging microscopyLive cell imagingMutantCellBiochemistryBiologyQuantum mechanicsOpticsPhysicsGeneOrganic chemistryGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyMetabolism and Genetic Disorders
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