Neurofibromatosis in the Era of Precision Medicine: Development of MEK Inhibitors and Recent Successes with Selumetinib
Robert Galvin, Adrienne L. Watson, David A. Largaespada, Nancy Ratner, Sara H. Osum, Christopher L. Moertel
Topics & Concepts
MedicineSelumetinibNeurofibromatosisMEK inhibitorTargeted therapyPrecision medicineNeurofibromaNeurofibromin 1OncologyInternal medicineCancer researchMAPK/ERK pathwayPathologyCancerKinaseKRASCell biologyColorectal cancerBiologyNeurofibromatosis and Schwannoma CasesSarcoma Diagnosis and TreatmentBone Tumor Diagnosis and Treatments