A dual drug-based hyperbranched polymer with methotrexate and chlorambucil moieties for synergistic cancer chemotherapy
Chengfei Liu, Huixin Li, Pengxiang Li, Caiping Liu, Yang Bai, Jun Pang, Jingxia Wang, Wei Tian
Abstract
Dual drug-based hyperbranched polymer micelles simultaneously containing methotrexate and chlorambucil were constructed for synergistic cancer chemotherapy.
Topics & Concepts
ChlorambucilChemotherapyMethotrexateDrugCancer chemotherapyChemistryMicellePolymerPharmacologyMedicineOrganic chemistrySurgeryAqueous solutionCyclophosphamideDendrimers and Hyperbranched PolymersClick Chemistry and ApplicationsRNA Interference and Gene Delivery