One-year aerobic exercise altered cerebral vasomotor reactivity in mild cognitive impairment
Tsubasa Tomoto, Takashi Tarumi, Jason N. Chen, Linda S. Hynan, C. Munro Cullum, Rong Zhang
Abstract
One-year moderate-to-vigorous intensity aerobic exercise training (AET) improved cardiorespiratory fitness (V̇o 2peak ), increased hypocapnic cerebral vasomotor reactivity (CVMR), whereas it decreased hypercapnic CVMR when compared with stretching and toning in patients with amnestic mild cognitive impairment (MCI). Furthermore, changes in hypercapnic CVMR with AET were correlated with improved memory and executive function. These findings indicate that AET has an impact on cerebrovascular function which may benefit cognitive performance in older adults who have high risk of Alzheimer’s disease.
Topics & Concepts
VasomotorAerobic exerciseCognitive impairmentMedicinePhysical exerciseCognitionPhysical medicine and rehabilitationPhysical therapyInternal medicineCardiologyNeurosciencePsychologyCardiovascular Health and Disease PreventionHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiology