Recurrent Glomerular Disease after Kidney Transplantation
Audrey Uffing, Frank Hullekes, Leonardo V. Riella, Jonathan J. Hogan
Abstract
Recurrent glomerular disease after kidney transplant remains an important cause of allograft failure. Many of the different entities post-transplant still suffer from incomplete knowledge on pathophysiology, and therefore lack targeted and effective therapies. In this review, we focus on specific clinical dilemmas encountered by physicians in managing recurrent glomerular disease by highlighting new insights into the understanding and treatment of post-transplant focal segmental glomerulosclerosis, membranous nephropathy, atypical hemolytic uremic syndrome, C3 glomerulopathy, amyloid light-chain (AL) amyloidosis, and IgA nephropathy.
Topics & Concepts
MedicineAmyloidosisFocal segmental glomerulosclerosisDiseaseTransplantationGlomerulopathyMembranous nephropathyKidney transplantationNephropathyPathologyGlomerulonephritisKidneyIntensive care medicineInternal medicineEndocrinologyDiabetes mellitusRenal Diseases and GlomerulopathiesRenal Transplantation Outcomes and TreatmentsComplement system in diseases