Therapeutic and prophylactic effects of macrophage-derived small extracellular vesicles in the attenuation of inflammatory pain
Renée Jean‐Toussaint, Zhucheng Lin, Yuzhen Tian, Richa Gupta, Richa Pande, Xuan Luo, Huijuan Hu, Ahmet Saçan, Seena K. Ajit
Topics & Concepts
MicrogliaLipopolysaccharideMedicineChronic painImmune systemPharmacologyAdjuvantHyperalgesiaDownregulation and upregulationAnalgesicProinflammatory cytokineInflammationStimulationFreund's adjuvantImmunologyNociceptionAnesthesiaBiologyInternal medicineReceptorBiochemistryPsychiatryGeneExtracellular vesicles in diseaseAdenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms