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Sunitinib induces cardiotoxicity through modulating oxidative stress and Nrf2-dependent ferroptosis in vitro and in vivo

Dongjie Li, Chengzhu Song, Chunpu Song, Xinrui Tian, Huaibo Zhang, Jie Zhang, Xiaoyan Zhao, Xiaoyan Zhao

2023Chemico-Biological Interactions20 citationsDOI

Topics & Concepts

CardiotoxicityIn vivoOxidative stressPharmacologyChemistryGlutathioneIn vitroInternal medicineBiologyMedicineToxicityBiochemistryEnzymeBiotechnologyFerroptosis and cancer prognosisCircular RNAs in diseasesRNA modifications and cancer
Sunitinib induces cardiotoxicity through modulating oxidative stress and Nrf2-dependent ferroptosis in vitro and in vivo | Litcius