Programmed Cell Death-1 (PD-1) anchoring to the GPI-linked co-receptor CD48 reveals a novel mechanism to modulate PD-1-dependent inhibition of human T cells
Della White, Alexandra Cote-Martin, Marina Bleck, Nicole Garaffa, Abdulsalam Shaaban, Helen L. Wu, Dongmei Liu, David Young, Justin K. Scheer, Ivo C. Lorenz, Andrew E. Nixon, Jay S. Fine, Fergus R. Byrne, M. Lamine Mbow, Miguel E. Moreno‐García
Topics & Concepts
Jurkat cellsCell biologyReceptorProto-oncogene tyrosine-protein kinase SrcT cellT-cell receptorNFATChemistrySignal transductionBiologyImmune systemBiochemistryImmunologyTranscription factorGeneImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology