Intravenous to Oral Switch in Complicated <i>Staphylococcus aureus</i> Bacteremia Without Endovascular Infection: A Retrospective Single-Center Cohort Study
Ilse J.E. Kouijzer, Eline J. van Leerdam, Michelle Gompelman, Renée A M Tuinte, Erik H.J.G. Aarntzen, Marvin A. H. Berrevoets, Ianthe Maat, Chantal P. Bleeker‐Rovers, Reinout van Crevel, Jaap ten Oever
Abstract
In this retrospective cohort study, selected patients with disseminated Staphylococcus aureus bacteremia, but without endovascular infection on echocardiography and 18F-FDG-PET/CT, were free of relapse after IV-oral switch. Mortality was low and similar to patients who received prolonged intravenous treatment. IV-oral switch was associated with a shorter length of hospital stay.
Topics & Concepts
MedicineBacteremiaRetrospective cohort studyStaphylococcus aureusCohortSingle CenterSurgeryBloodstream infectionStaphylococcal infectionsMethicillin-resistant Staphylococcus aureusCohort studyMicrococcaceaeInternal medicineAntibioticsMicrobiologyBiologyBacteriaGeneticsInfective Endocarditis Diagnosis and ManagementAntimicrobial Resistance in StaphylococcusCentral Venous Catheters and Hemodialysis