A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells
Niamh Moriarty, Carlos W. Gantner, Cameron J. Hunt, Charlotte M. Ermine, Stefano Frausin, Serena Viventi, Dmitry A. Ovchinnikov, Deniz Kirik, Clare L. Parish, Lachlan H. Thompson
Topics & Concepts
BiologyStriatumDopamineInduced pluripotent stem cellNeuroscienceMidbrainTransplantationGlial cell line-derived neurotrophic factorStem cellCell biologyCentral nervous systemNeurotrophic factorsEmbryonic stem cellGeneInternal medicineReceptorMedicineBiochemistryPluripotent Stem Cells ResearchNerve injury and regenerationCRISPR and Genetic Engineering