Astaxanthin mediated regulation of VEGF through HIF1α and XBP1 signaling pathway: An insight from ARPE-19 cell and streptozotocin mediated diabetic rat model
Rajasekar Janani, R Anitha, Madan Kumar Perumal, Peethambaran Divya, Vallikannan Baskaran
Topics & Concepts
AstaxanthinDownregulation and upregulationBlood–retinal barrierXBP1StreptozotocinVascular endothelial growth factorChemistryDiabetic retinopathyCell biologyRetinalEndocrinologyBiologyCancer researchBiochemistryDiabetes mellitusVEGF receptorsRNACarotenoidGeneRNA splicingRetinal Diseases and TreatmentsAntioxidant Activity and Oxidative StressBarrier Structure and Function Studies