Advanced Glycation End Products and Their Involvement in Cardiovascular Disease
Elena M. Yubero‐Serrano, Pablo Pérez-Martínez
Abstract
Circulating levels and tissue accumulation of advanced glyca-tion end products (AGEs) are strongly linked with metabolicimbalance and the progression of chronic diseases, includingcardiovascular disease (CVD). 1,2 Diet is the most importantexogenous source of AGEs contributing to the total body AGEsload. Experimental and clinical evidence suggests that thereduction in body AGE content, by dietary AGE restriction,could modulate different pathways involved in the pathophy-siology of CVD
Topics & Concepts
MedicineGlycationDiseaseAdvanced glycation end-productIntensive care medicineInternal medicineCardiologyDiabetes mellitusEndocrinologyAdvanced Glycation End Products researchNatural Antidiabetic Agents StudiesFatty Acid Research and Health