Satellite cell and myonuclear accretion is related to training-induced skeletal muscle fiber hypertrophy in young males and females
Sidney Abou Sawan, Nathan Hodson, Paul Babits, Julia M. Malowany, Dinesh Kumbhare, Daniel R. Moore
Abstract
We demonstrate that training-induced increase in SC content in type II fibers and myonuclear content in type I and II fibers is similar between males and females. Furthermore, these changes are related to the extent of muscle fiber hypertrophy. Thus, SC and myonuclear accretion appear to contribute to muscle hypertrophy irrespective of sex, highlighting the importance of these muscle stem cells in human skeletal muscle growth.
Topics & Concepts
Muscle hypertrophyInternal medicineResistance trainingEndocrinologySkeletal muscleFiberMedicineBiologyChemistryOrganic chemistryMuscle Physiology and DisordersMuscle metabolism and nutritionSpaceflight effects on biology