A phosphine free, inorganic base free, one-pot tandem Mizoroki–Heck olefination/direct arylation/hydrogenation sequence, to give multicyclic alkylated heteroarenes
Roberta A. Kehoe, Mark E. Light, David J. Jones, Gerard P. McGlacken
Abstract
One-pot processes which facilitate a number of tandem reactions, represent an environmentally friendly approach to building molecular complexity.
Topics & Concepts
TandemPhosphineChemistryAlkylationBase (topology)Sequence (biology)Combinatorial chemistryEnvironmentally friendlyHeck reactionOrganic chemistryPalladiumCatalysisMathematicsMaterials scienceEcologyComposite materialBiochemistryBiologyMathematical analysisAsymmetric Hydrogenation and CatalysisCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods