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Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

Paul Lacaze, Robert Sebra, Moeen Riaz, Jane Tiller, Jerico Revote, James Phung, Emily Parker, Suzanne G. Orchard, Jessica E. Lockery, Rory Wolfe, Maya Strahl, Ying C. Wang, Rong Chen, Daniel Sisco, Todd W. Arnold, Bryony A. Thompson, Daniel D. Buchanan, Finlay Macrae, Paul A. James, Walter P. Abhayaratna, Trevor Lockett, Peter Gibbs, Andrew Tonkin, Mark Nelson, Christopher M. Reid, Robyn L. Woods, Anne M. Murray, Ingrid Winship, John J. McNeil, Eric E. Schadt

2020Genetics in Medicine30 citationsDOIOpen Access PDF

Topics & Concepts

PenetranceMedicineMSH6PopulationLynch syndromeMedical geneticsDiseasePCSK9Internal medicineCancerGeneticsBiologyColorectal cancerGeneDNA mismatch repairEnvironmental healthPhenotypeLDL receptorLipoproteinCholesterolGenomics and Rare DiseasesBRCA gene mutations in cancerGenetic Associations and Epidemiology
Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals | Litcius