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Selective C–H Iodination of (Hetero)arenes

Lalita Tanwar, Jonas Börgel, Johannes Lehmann, Tobias Ritter

2021Organic Letters43 citationsDOIOpen Access PDF

Abstract

Iodoarenes are versatile intermediates and common synthetic targets in organic synthesis. Here, we present a strategy for selective C-H iodination of (hetero)arenes with a broad functional group tolerance. We demonstrate the utility and differentiation to other iodination methods of supposed sulfonyl hypoiodites for a set of carboarenes and heteroarenes.

Topics & Concepts

ChemistryHalogenationCombinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryVanadium and Halogenation ChemistryOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods
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