Cholesterol sensing by the SCAP–FAM134B complex regulates ER-phagy and STING innate immunity
Boran Li, Dongheng Zhou, Xinyi Wang, Xiao Jiang, Yongjuan Sang, Youjing Dai, Yao Yu, Yi Zhang, Chen Chen, Shulin Li, Ni Wang, Quan Zhou, Aifu Lin, Xinyang Hu, Liang Ge, Zhi‐Ying Wu, Pinglong Xu, Dante Neculai, Wei Liu, Qiming Sun
Topics & Concepts
CholesterolInnate immune systemEndoplasmic reticulumDownregulation and upregulationCell biologyRegulatorSignallingImmune systemBiologyImmunityStingSignal transductionChemistryReceptorState (computer science)Liver X receptorMechanism (biology)Reverse cholesterol transportOxysterolinterferon and immune responsesInflammasome and immune disordersImmune Cell Function and Interaction