Litcius/Paper detail

The involvement of the central nervous system in patients with COVID-19

Kiarash Saleki, Mohammad Banazadeh, Amene Saghazadeh, Nima Rezaei

2020Reviews in the Neurosciences109 citationsDOIOpen Access PDF

Abstract

Coronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)PandemicOutbreakCentral nervous systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Disease2019-20 coronavirus outbreakCoronavirusMedicineNeuroscienceNervous systemVirologyBiologyInfectious disease (medical specialty)PathologyLong-Term Effects of COVID-19COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research